Roster
| Slot | Player | Eligible Positions |
|---|---|---|
| QB | Justin Herbert | QB |
| WR | Tetairoa McMillan | WR, W/R/T |
| WR | DJ Moore | WR, W/R/T |
| RB | Breece Hall | RB, W/R/T |
| RB | Christian McCaffrey | RB, W/R/T |
| TE | Evan Engram | TE, W/R/T |
| W/R/T | Alvin Kamara | RB, W/R/T |
| K | Joshua Karty | K |
| DEF | Seattle | DEF |
| D | Brian Branch | D |
| BN On Bench | Jakobi Meyers | WR, W/R/T |
| BN On Bench | Puka Nacua | WR, W/R/T |
| BN On Bench | Chris Godwin Jr. | WR, W/R/T, IR |
| IR IR | Darren Waller | TE, W/R/T, IR |